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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NFE2L2
All Species:
15.45
Human Site:
Y226
Identified Species:
37.78
UniProt:
Q16236
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16236
NP_001138884.1
605
67827
Y226
K
L
T
E
V
D
N
Y
H
F
Y
S
S
I
P
Chimpanzee
Pan troglodytes
XP_001145876
712
78558
Y333
K
L
T
E
V
D
N
Y
H
F
Y
S
S
I
P
Rhesus Macaque
Macaca mulatta
XP_001096024
730
81414
Y350
K
L
T
E
V
D
N
Y
H
F
Y
S
S
I
S
Dog
Lupus familis
XP_535975
601
67199
Y222
M
T
E
I
D
N
N
Y
H
F
Y
P
S
M
P
Cat
Felis silvestris
Mouse
Mus musculus
Q60795
597
66883
S217
A
T
L
T
E
M
D
S
N
Y
H
F
Y
S
S
Rat
Rattus norvegicus
O54968
604
67684
S224
A
T
L
T
E
M
D
S
N
Y
H
F
Y
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515289
985
108157
P619
K
S
G
A
A
D
R
P
Y
G
F
Y
D
V
L
Chicken
Gallus gallus
Q5ZL67
772
85168
Q361
A
P
N
T
P
I
N
Q
N
V
S
L
H
Q
A
Frog
Xenopus laevis
NP_001086307
591
66538
Y225
M
T
E
S
P
D
T
Y
S
F
L
N
P
L
S
Zebra Danio
Brachydanio rerio
NP_878309
586
65869
Q212
P
S
T
E
A
P
T
Q
N
Y
S
Q
Y
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.7
81
87.2
N.A.
81.1
82.8
N.A.
29.1
26.9
52
45.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
77.6
81.2
90.9
N.A.
88.4
89.9
N.A.
41
43.3
69
62.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
46.6
N.A.
0
0
N.A.
13.3
6.6
20
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
60
N.A.
26.6
26.6
N.A.
33.3
13.3
33.3
40
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
30
0
0
10
20
0
0
0
0
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
50
20
0
0
0
0
0
10
0
0
% D
% Glu:
0
0
20
40
20
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
50
10
20
0
0
0
% F
% Gly:
0
0
10
0
0
0
0
0
0
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
40
0
20
0
10
0
0
% H
% Ile:
0
0
0
10
0
10
0
0
0
0
0
0
0
30
0
% I
% Lys:
40
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
30
20
0
0
0
0
0
0
0
10
10
0
20
10
% L
% Met:
20
0
0
0
0
20
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
10
0
0
10
50
0
40
0
0
10
0
0
0
% N
% Pro:
10
10
0
0
20
10
0
10
0
0
0
10
10
0
40
% P
% Gln:
0
0
0
0
0
0
0
20
0
0
0
10
0
10
0
% Q
% Arg:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% R
% Ser:
0
20
0
10
0
0
0
20
10
0
20
30
40
20
40
% S
% Thr:
0
40
40
30
0
0
20
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
30
0
0
0
0
10
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
50
10
30
40
10
30
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _